MBL Scientists Find Genes Linked to Human Neurological Disorders in Sea Lamprey Genome

February 27th, 2013 @   - 

Discovery will accelerate research on Alzheimer’s disease,

Parkinson’s disease and spinal cord injury

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MBL, WOODS HOLE, Mass. Scientists at the Marine Biological Laboratory (MBL) have identified several genes linked to human neurological disorders, including Alzheimer’s disease, Parkinson’s disease and spinal cord injury, in the sea lamprey, a vertebrate fish whose whole-genome sequence is reported this week in the journal Nature Genetics.

“This means that we can use the sea lamprey as a powerful model to drive forward our molecular understanding of human neurodegenerative disease and neurological disorders,” says Jennifer Morgan of the MBL’s Eugene Bell Center for Regenerative Biology and Tissue Engineering. The ultimate goals are to determine what goes wrong with neurons after injury and during disease, and to determine how to correct these deficits in order to restore normal nervous system functions…

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