Laboratory of Rudolf Oldenbourg

Rudolf Oldenbourg, Senior Scientist
Cellular Dynamics Program
Phone (508) 289-7426
Fax (508) 289-7579
E-Mail rudolfo@mbl.edu
Address MBL, 7 MBL Street, Woods Hole, MA 02543

 

LAB MEMBERS:
Rudolf Oldenbourg, Senior Scientist
Shalin Mehta, HFSP Postdoctoral Fellow
Mai Tran, Graduate student, Brown University
Grant Harris, Scientific Informatics Analyst I
Amitabh Verma, Scientific Informatics Analyst I

RESEARCH INTERESTS:
Our research is inspired by advanced optical methods to study the architectural dynamics in living cells. We are developing a new type of polarized light microscope, the LC-PolScope, for the analysis of molecular order directly in living cells with unprecedented sensitivity, resolution, and speed. Based on polarization measurements, we gain insight into submicroscopic structural parameters and non-invasively create contrast where native structures are otherwise invisible. We seek interdisciplinary collaborations to conduct research in physical optics for the interpretation of image content and in computational methods for image enhancement and restoration. These physical and engineering projects are stimulated and guided by biological inquiries into the structural basis of cell function.

LAB PROJECTS:
OpenPolScope
Polarized Light Field Imaging

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