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An intensive six-week laboratory and lecture course for advanced graduate students, postdoctoral fellows, and more senior researchers who seek a broad and balanced view of the modern issues of developmental biology. Limited to 24 students.
The integrated lectures and laboratories provide a comprehensive coverage of the paradigms, problems, and technologies of modern developmental biology, cast within a framework of metazoan evolution. Students are exposed to a wide variety of embryonic systems, including intensively studied genetic model systems ( e.g. C. elegans , Drosophila , zebrafish mouse) and others with well-established experimental attributes ( e.g. chick, sea urchins, frogs, ascidians). In addition, students will be introduced to a wide range of emerging systems, including locally available marine organisms, that help fill in the evolutionary history of animal diversity ( e.g. cnidarians, nemerteans, planaria, crustaceans, mollusks, and annelids) and that are becoming established as experimental systems in their own right. This broad coverage of metazoan phylogeny allows for the analyses of the developmental strategies that drive evolutionary change. Analytical and experimental techniques used to explore invertebrate and vertebrate development include embryological manipulation (e.g. cell ablation, tissue grafting), molecular genetic ( e.g. RNAi, electroporation) and cell biology approaches ( e.g. analysis of cell lineage and migratory behaviour), and microscopic and imaging technologies (e.g. confocal and 3-D time lapse), using state-of-the-art instrumentation and methodology. Conceptual topics include cell specification and differentiation, pattern formation, embryonic axis formation, morphogenesis, intercellular signaling, transcriptional regulation, organogenesis, and modern comparative embryology.
This course is supported with funds provided by
National Institute of Child Health and Human Development, NIH
Howard Hughes Medical Institute
Company of Biologists Ltd.
Society for Developmental Biology
2009 Faculty and Lecturers:
Sharon Amacher, University of California, Berkeley
Bruce Appel, University of Colorado Denver
Clare Baker, University of Cambridge
Richard Behringer, MD Anderson Cancer Center
Alexa Bely, University of Maryland
Andrea Brand, University of Cambridge
Andres Collazo, House Ear Institute
Cassandra Extavour, Harvard University
David Fitch, New York University
Richard Harland, University of California, Berkeley
Jonathan Henry, Univerisity of Illinois
Raymond Keller, University of Virginia
Michael Levin, Tufts University
Mike Levine, University of California, Berkeley
Amy Maddox, University of Montr?al
Paul Maddox, University of Montr?al
Terry Magnuson, University of North Carolina, Chapel Hill
Mark Martindale, University of Hawaii
David McClay, Duke University
Margaret McFall-Ngai, University of Wisconsin-Madison
Scott Nichols, University of California, Berkeley
Olivier Pourquie, Stowers Institute for Medical Research
Matthew Ronshaugen, University of Manchester
Dennis Roop, University of Colorado Denver
Joel Rothman, University of California, Santa Barbara
Alejandro Sanchez Alvarado, University of Utah Medical School
Alexander Schier, Harvard University
Elaine Seaver, University of Hawaii
Michael Shapiro, University of Utah
David Sherwood, Duke University
Stephen Small, New York University
Lori Sussel, University of Colorado Health Sciences
Paul Trainor, Stowers Institute for Medical Research
Robert Zeller, San Diego State University
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