Zebrafish Development and Genetics


Course Date: August 7 – August 20, 2016

Extended Deadline: May 3, 2016 | Apply here

2016 Schedule

Course Website

Directors: Corinne Houart, Kings College, UK; Sharon Amacher, The Ohio State University; and Erez Raz, University of Münster

Over the past 20 years, the zebrafish has emerged as a powerful model system for the study of vertebrate development and disease. This intensive two-week course for advanced graduate students, postdoctoral fellows, and independent investigators will focus on the development and genetics of zebrafish. The course will cover time proven as well as novel technologies geared towards their application in zebrafish. Mornings and afternoons will be devoted mainly to laboratory exercises and the evenings to lectures and discussion. Limited to 22 students.

Lectures and labs in the first week will introduce students to early development of the zebrafish and to methods for manipulating and studying gene function, including genetic and small molecule screening, mapping and cloning; mRNA overexpression and functional knockdown approaches; cell fate mapping; mounting and imaging of antibody and in situ samples for publication ready documentation. In the second week, students will be introduced to labeling and visualizing individual cells, photoconversion and live cell imaging, cell transplantation/chimera analysis, and to performing behavioral tests on live animals. Informal ‘roundtable’ discussions held periodically during the course include the design and execution of mutant screens/reverse genetics, transgenesis and zebrafish breeding and husbandry.

Each laboratory exercise will be under the supervision of a senior faculty member who will be assisted by one or two junior faculty members. Senior faculty will give research lectures about their work, in addition to leading discussions on topics covered in the course.

This course is supported with funds and equipment provided by:
Howard Hughes Medical Institute
National Institute of Neurological Disorders and Stroke
National Institute on Deafness and Other Communication Disorders
National Institute of Mental Health
National Institute on Drug Abuse
National Institute of Child Health and Human Development

2016 Course Faculty and Lecturers:

Sharon Amacher (Ohio State University)
Christine Beattie (Ohio State University)
Andres Collazo (Caltech)
Elena Dreosti (University College London)
Jim Fadool (Florida State University)
Steven Farber (Carnegie Institute)
Michael Granato (University of Pennsylvania)
Scott Holley (Yale University)
Corinne Houart (Kings College London)
Rolf Karlstrom (University of Massachusetts)
Cecilia Moens (Fred Hutchinson Cancer Research Center)
Ferenc Müller (University of Birmingham)
Mary Mullins (University of Pennsylvania)
Kenneth Poss (Duke University)
Dave Raible (University of Washington)
Erez Raz (Universitätsklinikum Münster)
Alex Schier (Harvard University)
Lila Solnica-Krezel (Washington University)
Debbie Yelon (University of California San Diego)