| Thursday, July 22 |
| 8:30 – 8:45 |
Introduction to the Program |
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Dr. Joshua Lederberg |
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| 8:45 – 9:15 |
Peter Palese, Ph.D. (SS), Mount Sinai School of Medicine |
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Cellular Genes and Viruses: Who Wins The War? |
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| 9:15 – 9:45 |
Alexander Rich, M.D. (SS), Massachusetts Institute of Technology |
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Viral Pathogenic Mechanisms Involving Z-DNA Binding Proteins |
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| 9:45 – 10:15 |
Coffee Break |
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| 10:15 – 10:45 |
Christopher Basler, Ph.D. (NS), Mount Sinai School of Medicine |
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Emerging viruses: interferon antagonists and virulence |
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| 10:45 – 11:15 |
Philip Ralph Dormitzer, M.D., Ph.D. (NS), Children’s Hospital, Boston |
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Structure-based Approach to Rotavirus Vaccine Design and Cell Entry |
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| 11:15 – 11:45 |
Keril J. Blight, Ph.D. (NS), Washington University |
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Characterization of the NS4B Protein in Hepatitis C Virus |
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| 11:45 AM – 1:00 |
Lunch |
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| 1:00 – 1:30 |
Marc Lipsitch, D. Phil. (NS), Harvard School of Public Health |
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Antibiotic Resistance in Streptococcus pneumoniae: Transmission Dynamics and Consequences for Public Health |
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| 1:30 - 2:00 |
Pejman Rohani, Ph.D. (NS), University of Georgia Research Foundation, Inc. |
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The Ecology and Evolution of Disease Interference
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| 2:00 – 2:30 |
Lee W. Riley, M.D. (SS), University of California, Berkeley |
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Mycobacterium tuberculosis Latency and Reactivation Tuberculosis |
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| 2:30 - 3:00 |
Michael S. Glickman, M.D. (NS), Memorial Sloan-Kettering Cancer Center |
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Coordinate Regulation of M. tuberculosis Cell Envelope Composition during Symbiosis |
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| 3:00 - 3:30 |
Coffee Break |
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| 3:30 - 4:00 |
Michael D. Burkart, Ph.D. (NS), University of California, San Diego |
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Biosynthetic Inhibition of Small Molecule Virulence Factors from Mycobacteria |
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| 4:00 - 4:30 |
Laurie H. Glimcher, M.D. (SS), Harvard School of Public Health |
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Arming the Immune System against Pathogens with Selective Biologics: The Next Generation of Vaccines |
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| 4:30 - 5:00 |
Carl Nathan, M.D. (SS), Weill Medical College of Cornell University |
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Genomic Approach to Improved Immunogenicity of M. tuberculosis |
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| Friday, July 23 |
| 8:30 – 9:00 |
Eleftherios Mylonakis, M.D., Ph.D. (NS), Massachusetts General Hospital |
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Use of the Caenorhabditis elegans Model of Fungal Pathogenesis to Identify Virulence Factors of the Pathogenic Yeast Cryptococcus neoformans |
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| 9:00 – 9:30 |
Ernesto Abel-Santos, Ph.D. (NS), Albert Einstein College of Medicine of Yeshiva University |
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Peptide Modulators of Bacterial Cell Differentiation |
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| 9:30 – 10:00 |
Coffee Break |
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| 10:00 – 10:30 |
Jeffrey I. Gordon, M.D. (SS), Washington University School of Medicine |
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A Gnotobiotic Zebrafish Model for Analyzing Symbiotic Host-bacterial Interactions in the Mammalian Gut |
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| 10:30 – 11:00 |
Abigail A. Salyers, Ph.D. (SS), University of Illinois at Urbana-Champaign |
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Resistance Gene Flow in the Human Colonic Microflora |
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| 11:00 – 11:30 |
Roy Curtiss, III, Ph.D. (SS), Washington University |
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Providing an Economic Benefit to Using a Vaccine to Enhance Food Safety and to Reduce Antibiotic Use in Agriculture |
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| 11:30 – 1:00 |
Lunch |
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| 1:00 – 1:30 |
Fitnat Yildiz, Ph.D. (NS), University of California, Santa Cruz |
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Environmental Factors that Modulate Biofilm Formation Dynamics in Vibrio cholerae O1 E1 Tor |
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| 1:30 – 2:00 |
Roberto G. Kolter, Ph.D. (SS), Harvard Medical School |
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Ecological Influences on Pathogen Genome Evolution |
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| 2:00 – 2:30 |
Coffee Break |
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| 2:30 – 3:00 |
Kent Hill, Ph.D. (NS), University of California, Los Angeles |
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Mechanism and Biology of Trypanosome Cell Motility: Contribution to Parasite Development and Disease Pathogenesis |
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| 3:00 – 3:30 |
Yasmine Belkaid, Ph.D. (NS), University of Cincinnati College of Medicine |
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Latency, Reactivation and Immunity in Chronic Parasitic Disease |
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| 3:30 – 4:00 |
Kristin M. Hager, Ph.D. (NS), University of Notre Dame |
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Analysis of Membrane Trafficking Events in the Regulation of Organelle Biogenesis and Stability in Apicomplexan Parasites |
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| 4:00 – 4:30 |
John C. Boothroyd, Ph.D. (SS), Stanford University School of Medicine |
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Evolution of Virulence in Eukaryotic Pathogens |
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| 8:00 PM |
Friday Evening Lecture - Arnold Levine, Ph.D. |
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Institute for Advanced Study and Robert Wood Johnson School of Medicine
Genetic Predispositions for Cancers in Humans
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| Saturday, July 24 |
| 8:30 – 9:00 |
David S. Schneider, Ph.D. (NS), Stanford University |
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Dissecting Malaria Vector-pathogen Interactions using a Drosophila-Plasmodium Genetic System |
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| 9:00 – 9:30 |
Kirk W. Deitsch, Ph.D. (NS), Weill Medical College of Cornell University |
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DNA Replication and var Gene Expression in Plasmodium falciparum |
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| 9:30 – 10:00 |
Ronald P. Taylor, Ph.D. (SS), University of Virginia |
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Investigation of Mechanisms Leading to Anemia at Low Parasite Burden in Children with Malaria |
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| 10:00 – 10:30 |
Coffee Break |
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| 10:30 – 11:00 |
Ali A. Sultan, M.D., Ph.D. (NS), Harvard School of Public Health |
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Molecular Mechanisms of Plasmodium Sporozoite Pathogenicity |
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| 11:00 – 11:30 |
Daniel L. Hartl, Ph.D. (SS), Harvard University |
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Conditional Targeted Deletions in Plasmodium falciparum |
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| 11:30 – 12:00 |
Pradipsingh K. Rathod, Ph.D. (SS), University of Washington |
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Genomic tools to characterize hypermutating Plasmodium falciparum |
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| 12:00 – 12:30 |
David S. Roos, Ph.D. (SS), University of Pennsylvania |
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Designing and Mining Pathogen Genome Databases: The Apicoplast as a Novel Drug Target in Plasmodium Parasites…and Other Stories |
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