| Thursday, August 17 |
| 8:15 - 8:30 |
Introductions |
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| 8:30 - 9:05 |
Jacob Raber, Ph.D.
The Oregon Health & Science University
Gender and Isoform-Specific Effects of ApoE on Cognition in Humans
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| 9:05 - 9:40 |
Michael Gordon Kaplitt, M.D., Ph.D.
Weill Medical College of Cornell University
Effect of PTEN Anti-Oncogene on Age-Related Neurodegenerative Disorders
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| 9:40 - 10:15 |
Ya Ha, Ph.D.
Yale University School of Medicine
Structural basis of intramembrane proteolysis: implications for Alzheimer's gamma-secretase
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| 10:15 – 10:45 |
Break |
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| 10:45 – 11:20 |
Rudolph E. Tanzi, Ph.D.
Massachusetts General Hospital
Role of the Multiligand Receptor LRP in Alzheimer’s Disease-Related Neuropathogenesis: A Model for Age-Related Disorders Involving LRP
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| 11:20 - 11:55 |
Tae-Wan Kim, Ph.D.
Columbia University
Genetic Studies of Factors Controlling Amyloid Production
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| 11:55 – 1:00 |
Lunch |
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| 1:00 – 1:35 |
Giovanni Paternostro, M.D., Ph.D.
The Burnham Institute
Genetic Analysis of Cardiac Aging in Drosophila: A Systems Biology Approach
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| 1:35 - 2:10 |
Thomas P. Sakmar, M.D.
The Rockefeller University
The Chromophore Regeneration Pathway in Age-Related Macular Degeneration
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| 2:10 - 2:40 |
Break |
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| 2:40 - 3:15 |
Brad A. Rikke, Ph.D.
University of Colorado at Boulder
QTLs Specifying the Retardation of Reproductive Senescence by Dietary Restriction
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| 3:15 - 3:50 |
Stephen Lyle, M.D., Ph.D.
University of Massachusetts Medical School
Molecular and Cell Biology of Adult Epithelial Stem Cells
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| Friday, August 18 |
| 8:00 – 8:35 |
Yidong Bai, Ph.D.
University of Texas Health Science Center at San Antonio
Molecular Remedy of Mitochondrial Deficiency
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| 8:35 - 9:10 |
Stephen L. Helfand, M.D.
Brown University
Genetic Dissection of Aging in Drosophila
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| 9:10 - 9:45 |
Cynthia J. Kenyon, Ph.D.
University of California, San Francisco
How Does Caloric Restriction Extend Lifespan?
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| 9:45 - 10:20 |
James F. Nelson, Ph.D.
University of Texas Health Science Center at San Antonio
A New Murine Model for Longevity Assurance Is Associated with Ethanol Tolerance
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| 10:20 - 10:50 |
Break |
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| 10:50 - 11:25 |
Gordon J. Lithgow, Ph.D.
The Buck Institute for Age Research
The Rapid Identification of Hormones and Pharmacological Compounds that Slow Aging in C. elegans
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| 11:25 - 12:00 |
Antonio Bedalov, M.D., Ph.D.
Fred Hutchinson Cancer Research Center
Chemical Genetic Approaches to Aging
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| 12:00 - 1:00 |
Lunch |
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| 1:00 - 1:35 |
Stuart Kim, Ph.D.
Stanford University Medical Center
Genomic approaches to studying aging in C. elegans
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| 1:35 - 2:10 |
Thomas Kornberg, Ph.D.
University of California, San Francisco
Toward a Comprehensive Assessment of Gene Expression during Development and Aging of Drosophila
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| 2:10 - 2:45 |
David Walker, Ph.D. / Seymour Benzer, Ph.D.
California Institute of Technology
Mitochondrial Dysfunction in Drosophila
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| 8:00 PM |
Friday Evening Lecture
Helen M. Blau, Ph.D.
Stanford University School of Medicine
Nuclear Reprogramming by Cell Fusion
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| Saturday, August 19 |
| 8:00 - 8:35 |
Ari Gafni, Ph.D.
University of Michigan
Structure Induction in Heat Shock Factor 1, A Natively Unfolded Transcription Factor
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| 8:35 - 9:10 |
Ana Maria Cuervo, M.D., Ph.D.
Albert Einstein College of Medicine
Restoration of Chaperone-Mediated Autophagy Activity in Old Rodents
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| 9:10 - 9:45 |
Simon Melov, Ph.D.
Buck Institute for Age Research
Critically Testing the Free Radical Theory of Aging, and Development of a Practical Intervention
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| 9:45 - 10:15 |
Break |
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| 10:15 - 10:50 |
Stanley N. Cohen, M.D.
Stanford University School of Medicine
Genetic Mechanisms Regulating Replicative Aging in Differentiated Human Cell Populations
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| 10:50 - 11:25 |
Woodring E. Wright, M.D., Ph.D.
The University of Texas Southwestern Medical Center at Dallas
Functional Tests of Replicative Aging in Organotypic Skin Equivalents
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