Section 3

Development and functions of the male and female reproductive tracts (Barry Hinton, Section Director)

Section 3 focuses on the examination of the developing and adult male and female reproductive tracts under normal and pathological conditions. Lectures cover transgenic technology including microinjection, stem cells, gene editing, and embryo transfer; development of the male and female reproductive tracts and gonads; maternal-fetal interactions including implantation, uterine decidualization, comparative placentation, placental function and immunological adaptations to pregnancy. Additional lectures cover topics of clinical relevance to the reproductive tract, such as implantation failure including metabolic consequences, endometriosis, prostate cancer and functions of the oviduct. The use of non-traditional species in advancing reproductive sciences such as domestic animals, wild animals and Drosophila melanogaster will be discussed. The labs in Section 3 focus on techniques associated with the lecture topics, including generation and characterization of transgenic embryos, the use of laser capture microdissection, in vitro models including cell and organ culture, flow cytometry, and reporter assays to evaluate function of the reproductive tract.

The schedule for Section 3 of FIR2017 can be downloaded here.