Complex “corn cobs” in dental plaque.  Plaque was collected from the surface of a volunteer’s tooth using a toothpick.  The plaque was then embedded in acrylic resin and sectioned to 2 microns thickness.  FISH was performed on the plaque using probes for Corynebacterium (magenta), Streptococcus (green), Aggregatibacter (orange), and Porphyromonas (blue).  Each tiny dot is an individual bacterial cell.  The Streptococcus cells form “corn cobs” surrounding Corynebacterium filaments, and Aggregatibacter cells surround some of the Streptococcus corn cobs.  Porphyromonas cells also form corn cobs around Corynebacterium filaments.

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