Select Publications

Delay, B.D., Corkins, M.E., Hanania, H.L., Salanga, M., Deng, J.M., Sudou, N., Taira, M., Horb, M.E. and Miller, R.K. (2018). Tissue-specific gene inactivation in Xenopus laevis: knockout of lhx1 in the kidney with CRISPR/Cas9. Genetics 208, 673-686. PubMed

Corkins, M.E., Hanania, H.L., Krneta-Stankic, V., DeLay, B.D., Pearl, E.J., Lee, M., Ji, H., Davidson, A.J., Horb, M.E. and Miller, R.K. (2018) Transgenic Xenopus laevis line for in vivo labeling of nephrons within the kidney. Genes 9, 197. PubMed

Tandon, P., Conlon, F., Furlow, D. and Horb, M.E. (2017). Expanding the genetic toolkit in Xenopus: approaches and opportunities for human disease modeling. Developmental Biology (in press). PubMed

Pearl E, Morrow S, Noble A, Lerebours A, Horb M, Guille M. (2017) An optimized method for cryogenic storage of Xenopus sperm to maximise the effectiveness of research using genetically altered frogs. Theriogenology. 92, 149-155. PubMed

Savova V, Pearl EJ, Boke E, Nag A, Adzhubei I, Horb M.E., Peshkin L. (2017) Transcriptomic insights into genetic diversity of protein-coding genes in X. laevis. Dev Biol. 424, 181-188. PubMed

Webb, B.D., Metikala, S., Wheeler, P.G., Sherpa, M.D., Houten, S.M., Horb, M.E. and Schadt, E.E. (2017). Heterozygous pathogenic variant in Dact1 causes an autosomal dominant syndrome with features overlapping Townes-Brocks syndrome. Human Mutation 38, 373-377. PubMed

Wlizla, M., Falco, R., Parlow, A.F. and Horb, M.E. (2017). Luteinizing Hormone is an effective replacement for hCG to induce ovulation in Xenopus. Developmental Biology 426, 442-448. PubMed

Ratzan, W., Falco, R., Salanga, C., Salanga, M. and Horb, M.E. (2017). Rapid generation of a Xenopus laevis F1 albino J strain by TALENs and oocyte host transfer. Developmental 426, 188-193. PubMed

Peshkin, L., Wühr, M., Pearl, E., Haas, W., Freeman, R.M. Jr., Gerhart, J., Klein, A., Horb, M., Gygi, S., Kirschner, M. (2015). On the Relationship of Protein and mRNA in Vertebrate Embryonic Development. Developmental Cell, 35(3), 383-394. PubMed

Salanga, M. C., & Horb, M. E. (2015). Xenopus as a Model for GI/Pancreas Disease. Current Pathobiology Reports, 3(2), 137–145. PubMed

Wuhr, M., Freeman, R.M. Jr., Presler, M., Horb, M.E., Peshkin, L., Gygi, S.P., Kirschner, M.W. (2014) Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database. Current Biology 24: 1467-1475. PubMed

Bilogan, C.K., and Horb, M.E. (2012) Xenopus staufen2 is required for anterior endodermal organ formation. Genesis 50: 251-259. PubMed

Bilogan, C.K. and Horb, M.E. (2012) Microarray analysis of Xenopus endoderm expressing Ptf1a. Genesis Jul 20, ePub. PubMed

Pearl, E.J., Grainger, R.M., Guille, M., Horb, M.E. (2012) Development of Xenopus resource centers: the National Xenopus Resource and the European Xenopus Resource Center. Genesis 50, 155-163. PubMed

Oropez, D. and Horb, M.E. (2012) Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells. Genesis 50, 271-285. PubMed

Pearl, E.J., Jarikji, Z., Horb, M.E. (2011) Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes. Dev. Biol. 351, 135-145. PubMed

Horb, L.D. and Horb, M.E. (2010) BrunoL1 regulates endoderm proliferation through translational enhancement of cyclin A2 mRNA. Dev. Biol. 345, 156-169. PubMed

Horb, L.D., Jarkji, Z.H., Horb, M.E. (2009) Xenopus insm1 is essential for gastrointestinal and pancreatic endocrine cell development. Dev. Dyn. 238, 2505-2510. PubMed

Jarikji, Z., Horb, L.D., Shariff, F., Mandato, C.A., Cho, K.W., Horb, M.E. (2009) The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. Development 136, 1791-1800. PubMed

Pearl, E.J., Bilogan, C.K., Mukhi, S., Brown, D.D., Horb, M.E. (2009) Xenopus pancreas development. Dev. Dyn. 238, 1271-1286. PubMed

Jarikji, Z.H., Vanamala, S., Beck, C.W., Wright, C.V., Leach, S.D., Horb, M.E. (2007) Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas. Dev. Bio. 304, 786-799. PubMed

Li, W.C., Horb, M.E., Tosh, D., Slack, J.M. (2005) In vitro transdifferentiation of hepatoma cells into functional pancreatic cells. Mech. Dev. 122, 835-847. PubMed

Horb, M.E., Shen, C.N., Tosh, D., Slack, J.M. (2003) Experimental conversion of liver to pancreas. Curr. Biol. 13, 105-115. PubMed

Shen, C.N., Horb, M.E., Slack, J.M., Tosh, D. (2003) Transdifferentiation of pancreas to liver. Mech. Dev. 120, 107-116. PubMed

Horb, M.E. and Slack, J.M. (2002) Expression of amylase and other pancreatic genes in Xenopus. Mech. Dev. 113, 153-157. PubMed

Horb, M.E., Slack, J.M. (2001) Endoderm specification and differentiation in Xenopus embryos. Dev. Bio. 236, 330-343. PubMed