Course Information

Course Date: May 31 – July 28, 2018

Deadline: February 1, 2018 | Apply here

Tuition: $6500.00
Room and Board: $4190.50

2017 Lecture Schedule (PDF)

Director: Diana Bautista, UC Berkeley

Course Description

An intensive and comprehensive laboratory-oriented course in cellular and molecular neurobiology intended for predoctoral students, postdoctoral or clinical researchers, and young investigators beginning independent research careers.

A hallmark of this course is the extensive lab work done in close collaboration with expert faculty. The course is divided into three sections: Electrophysiology, Imaging, and Molecular Neurobiology. These are taught by separate groups of faculty, usually six in each section, and with many guest lecturers. Each section begins with specific training in core laboratory techniques; students then undertake one- to two-week directed or independent projects using the methods they have learned. Didactic lectures are combined with laboratory experience in order to establish a strong conceptual foundation for each section. A typical day has 3 hours of lecture and 10 hours of lab.

Electrophysiological methods focus on patch-clamp and sharp electrode recordings, performed on neurons in a variety of preparations, including tissue culture, brain slices, isolated squid synapses, rat cochlea, or whole fish. Optical methods include calcium imaging, confocal and 2-photon microscopy, videomicroscopy, and electron microscopy. Molecular techniques emphasize the use of forward and reverse genetics in diverse systems such as Drosophila, C. elegans, zebrafish, chick embryos, and primary cells in culture. The impact of genetic manipulations are assayed by real time PCR, laser microdissection, single cell PCR, in situ hybridization, and a variety of immunotechniques in addition to incorporating electrophysiological and imaging techniques.

The goal of the course is to emphasize the strengths of a multidisciplinary approach for studying the function of the nervous system at the cellular and molecular levels.

2017 Course Faculty & Lecturers

Adler, Carolyn, Cornell University
Aizenman, Carlos, Brown University
Araneda, Ricardo, University of Maryland
Brockie, Penelope, University of Utah
Dhaka, Ajay, University of Washington
Douglass, Adam, University of Utah
Eaton, Benjamin, UTHSCSA
Firestein, Stuart, Columbia University
Garrison, Jennifer, Buck Institute
Gracheva, Elena, Yale University School of Medicine
Hammarlund, Marc, Yale University
Higley, Michael, Kacey Rajkovich
Hollopeter, Gunther, Cornell University
Hoppa, Michael, Dartmouth College
Jorgensen, Erik, University of Utah
Kanold, Patrick, University of Maryland
Kaun, Karla, Brown University
Lichtman, Jeff, Harvard University
Liman, Emily, University of Southern California
Logan, Mary, Oregon Health and Science University
Lumpkin, Ellen, Columbia University
MacKinnon, Roderick, Rockefeller University/HHMI
Morita, Takeshi, The Rockefeller University
Mueller, Martin, University of Zurich
Parrish, Jay, University of Washington
Peterka, Darcy, Columbia University
Pratt, Kara, University of Wyoming
Sack, Jon, University of California, Davis
Sandmann, Thomas, Denali Therapeutics
Schwarz, Thomas , Harvard University
Shroff, Hari, NIH
Speese, Sean, OHSU
Turrigiano, Gina, Brandeis University
Watanabe, Shigeki, Johns Hopkins University
Yasuda, Ryohei, Max Planck Florida Institute
Zito, Karen, University of California Davis
Zuo, Yi, UC Santa Cruz

Course Support

This course is supported with funds provided by:

National Institute of Mental Health, NIH
Howard Hughes Medical Institute
The Grass Foundation
International Brain Research Organization
Genentech, Inc.