National Xenopus Resource
Falmouth Enterprise article on CRISPR techniques used in the NXR. Read more
New discovery reveals evolutionary path from fins to fingers by using CRISPR/Cas gene editing techniques learned at the NXR. Read more
NXR study shows that LH can be used in place of hCG to induce ovulation in Xenopus. Read more
New paper from NXR and Horb lab showing efficient germline transmission of TALEN-induced mutations in X. laevis. Read article here
Review article on genome editing in Xenopus just published! Read review article here
The National Xenopus Resource (NXR) is located at the Marine Biological Laboratory (MBL) in Woods Hole, Massachusetts, and serves as a national stock center for X. laevis and X. tropicalis as well as a training center for advanced technologies (e.g. husbandry, cell biology, imaging, genetics, transgenesis, genomics). The NXR is funded by an award from the National Institute of Health, Office of the Director, Office of Research Infrastructure Programs (ORIP) and from the Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD).
The MBL is an international center for research, education, and training in biology, biomedicine, and ecology. Housed in the MBL’s Loeb Laboratory, the National Xenopus Resource is a cornerstone of the Eugene Bell Center for Regenerative Biology and Tissue Engineering. The NXR provides a facility for breeding X. laevis and X. tropicalis, maintaining genetic stocks, providing stocks to researchers, developing new experimental tools and husbandry techniques, and meeting other needs of the Xenopus research community through workshops and meetings. Input from the Xenopus research community regarding what genetic lines should be raised, and priorities for advanced research courses, is highly encouraged. Please send feedback to Xenopus@mbl.edu.