MBL courses are often called “transformative”, a strong statement, verified each year in course reviews. Why? Because students are empowered to pursue science at the very highest levels. Participants have access to state-of-the-art equipment and learn the fundamental principles upon which the technology is based. Trainees work directly with outstanding faculty from around the world, pursuing novel experiments that test new ideas and foster a globe-spanning network of collaboration. From this comes a fearlessness pushing the boundaries of current knowledge.