Eugene Bell Center for Regenerative Biology and Tissue Engineering
Research in the Center is intended to elucidate the molecular, genetic and cellular mechanisms underlying the growth and replacement of highly differentiated tissues during development, physiological turnover and repair following injury.
About the Eugene Bell Center
axolotl spinal cord image
Axolotl spinal cord. Credit: Sarah Walker
About Eugene Bell

The Eugene Bell Center for Regenerative Biology and Tissue Engineering is named in honor of Dr. Eugene Bell (1919 – 2007), a pioneer in the field of tissue engineering and a valued member of the Marine Biological Laboratory scientific community.

In the 1980s, Dr. Bell developed a method to grow human skin that could be grafted onto wounds of burn victims and other severely injured patients without rejection. He also devised ways to grow “skin equivalents” for blood vessels or organ tissue. His research led to what is now known as regenerative medicine.

Learn more about Dr. Bell and the Bell Center
Eugene Bell
Bell Center Symposium - June 2023
Bell center graphic

Please join us for the inaugural Bell Center Symposium where we will learn about the latest discoveries in areas including regenerative biology and tissue engineering, cell and developmental biology, neuroscience, imaging and more! Featuring a variety of model organisms, including marine and aquatic species.

learn more about the Bell center symposium
Shinya Inoué Symposium - July 2023
Easter Lily pollen, GFP Crystal, Sand dollar egg.

Join us for a Symposium celebrating the life of Shinya Inoué and his seminal contributions to cell biology. Everyone is welcomed. The program starts off in the morning with the Physiology course lecture by Jennifer Lippincott-Schwartz and continues into the afternoon with research talks by eminent cell biologists whose research is inspired by the legacy of Shinya Inoué. Research talks are followed by short testimonials and reminiscences by students and colleagues of Shinya Inoué. The program is rounded out by a panel discussion on the need for interdisciplinary spaces for the development, access, and training on advanced microscopy methods for biology. The discussion will be preceded by lightning talks on interdisciplinary research projects pursued by young scientists, including Physiology course students.

Learn more about the Inoue Symposium

Recent Publications

Avram-Shperling, A., Kopel, E., Twersky, I., Gabay, O., Ben-David, A., Karako-Lampert, S., Rosenthal, J. J. C., Levanon, E. Y., Eisenberg, E., & Ben-Aroya, S. (2023). Identification of exceptionally potent adenosine deaminases RNA editors from high body temperature organisms. PLOS Genetics, 19(3), e1010661.

Cai, L., McGuire, N. E., Hanlon, R., Mooney, T. A., & Girdhar, Y. (2023). Semi-supervised Visual Tracking of Marine Animals Using Autonomous Underwater Vehicles. International Journal of Computer Vision.

Diaz Quiroz, J., Ojha, N., Shayhidin, E., De Silva, D., Dabney, J., Lancaster, A., Coull, J., Milstein, S., Fraley, A., Brown, C., & Rosenthal, J. (2023). Development of a selection assay for small guide RNAs that drive efficient site-directed RNA editing. Nucleic Acids Research.

Hamlet, C., Fauci, L., Morgan, J. R., & Tytell, E. D. (2023). Proprioceptive feedback amplification restores effective locomotion in a neuromechanical model of lampreys with spinal injuries. Proceedings of the National Academy of Sciences, 120(11), e2213302120.

Martens, K., Shribak, M., Arkhipova, I., & Schön, I. (2023). The common morphospecies Cypridopsis vidua (O.F. MÜLLER, 1776) (Crustacea, Ostracoda) is not an obligate parthenogen. Belgian Journal of Zoology, 153(0), Article 0.

Diaz Quiroz, J., Siskel, L., & Rosenthal, J. (2023). Site-directed A→I RNA editing as a therapeutic tool: Moving beyond genetic mutations. RNA, rna.079518.122.

Rosenthal, J. J. C., & Eisenberg, E. (2023). Extensive Recoding of the Neural Proteome in Cephalopods by RNA Editing. Annual Review of Animal Biosciences, 11(1), 57–75.

Subramanian, E., Elewa, A., Brito, G., Kumar, A., Segerstolpe, Å., Karampelias, C., Björklund, Å., Sandberg, R., Echeverri, K., Lui, W.-O., Andersson, O., & Simon, A. (2023). A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration. Developmental Cell.

Walker, S., Santos-Ferreira, T., & Echeverri, K. (2023). A Reproducible Spinal Cord Crush Injury in the Regeneration-Permissive Axolotl. In A. J. Udvadia & J. B. Antczak (Eds.), Axon Regeneration: Methods and Protocols (pp. 237–246). Springer US.

Spurrell, M., Oulhen, N., Foster, S., Perillo, M., & Wessel, G. (2023). Gene regulatory divergence amongst echinoderms underlies appearance of pigment cells in sea urchin development. Developmental Biology, 494, 13–25.

[The final version of this paper is being published in the February 2023 issue of Developmental Biology]

Sterner, Z. R., Jabrah, A., Shaidani, N.-I., Horb, M. E., Dockery, R., Paul, B., & Buchholz, D. R. (2023). Development and metamorphosis in frogs deficient in the thyroid hormone transporter MCT8. General and Comparative Endocrinology, 331, 114179.

Shindyapina, A., V., Cho, Y., Kaya, A., Tyshkovskiy, A., Castro, J. P., Deik, A., Gordevicius, J., Poganik, J. R., Clish, C. B., Horvath, S., Peshkin, L., & Gladyshev, V. N. (2022). Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna. Science Advances, 8(37).

Echeverri, K. (2022). Zebrafishing for enhancers of hearing regeneration. Cell Genomics, 2(9), 100178.

Houston, D., Elliott, K., Coppenrath, K., Wlizla, M., & Horb, M. (2022). Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: Analysis of maternal-effect wnt11b mutants. Development, 149(17).

Drinkwater, E., Allen, W., Endler, J., Hanlon, R., Holmes, G., Homziak, N., Kang, C., Leavell, B., Lehtonen, J., Loeffler‐Henry, K., Ratcliffe, J., Rowe, C., Ruxton, G., Sherratt, T., Skelhorn, J., Skojec, C., Smart, H., White, T., Yack, J., Young, C. M. & Umbers, K. (2022). A synthesis of deimatic behaviour. Biological Reviews.

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MBL Through The Lens of Time :: Roger Hanlon
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Video credit: UnderCurrent Productions